Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin function
نویسندگان
چکیده
منابع مشابه
Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin function.
Heart formation requires the fusion of bilateral cardiomyocyte populations as they move towards the embryonic midline. The bHLH transcription factor Hand2 is essential for cardiac fusion; however, the effector genes that execute this function of Hand2 are unknown. Here, we provide in zebrafish the first evidence for a downstream component of the Hand2 pathway that mediates cardiac morphogenesis...
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ژورنال
عنوان ژورنال: Development
سال: 2010
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.052225